Get help today 888-287-0471 or sign up for 24/7 text support.
American Addiction Centers National Rehabs Directory


Xodol is a brand name pharmaceutical compound consisting of hydrocodone and acetaminophen. While hydrocodone is a strong narcotic drug designed to provide pain relief, acetaminophen – on its own a less potent pain medication – combines synergistically to create an even greater alleviation of pain and discomfort.
“Dosage of this drug should not exceed 1,000 mg per dose and 4,000 mg per day.”
Xodol is most often prescribed for pain ranging from moderate to severe, but it is also indicated for cases of persistent coughing. Commonly issued in tablet or capsule form and received orally, Xodol can be unintentionally abused if it enters the bloodstream after being crushed or chewed. Reception through the nose is also hazardous. Dosage of this drug should not exceed 1,000 mg per dose and 4,000 mg per day.

Physiological Effects of Xodol

Xodol addiction treatment begins with understanding the drug’s function. The human brain and spinal cord — the central nervous system — are populated with opioid receptors. These are essential in regulating neurotransmitters and hormones. Opioid receptors can be stimulated by chemical reactions within the body or by ingested opiate compounds like Xodol. Once activated by the hydrocodone, the receptors effectively neutralize pain. Meanwhile, the acetaminophen works to inhibit the development of prostaglandins, which are chemicals akin to hormones. Prostaglandins help to control smooth muscle contraction, the opening and closing of blood vessels, inflammation and blood pressure. Stifling their activity complements the pain reduction caused by the activated receptors.

Signs of Xodol Addiction

“Like all drugs that shut down pain, Xodol can be addictive.”
Like all drugs that shut down pain, Xodol can be addictive. The Centers for Disease Control and Prevention reported that in 2011, 76 percent of doctor visits involved some form of drug therapy. Also, according to the Council of Emergency Medicine Residency Directors, nearly 10 percent of physicians who prescribe opiate pain medicines become addicted to pain meeds themselves. Those experienced with Xodol addiction treatment recognize that a dependency has formed when the prescribed dosage fails to provide the same level of relief over time. Without increases in quantity, the addicted user begins to evidence withdrawal symptoms. These include:

  • Insomnia
  • Nervousness
  • Muscle and bone pain
  • Diarrhea
  • Vomiting
  • Involuntary limb movement

Should you or an acquaintance be experiencing any of these issues while taking Xodol, consider addiction treatment. Take the first step by calling .

Why Do People Abuse Xodol?

drug toleranceMost people do not set out to abuse Xodol. As with other narcotics, this drug solves an immediate problem, namely pain. However, long-term usage maximizes Xodol’s addictive properties. The euphoric feeling that it may induce serves to reduce anxiety and psychological dependence can soon follow. The fear of a return of acute pain also plays a role in unhealthy reliance. Most of all, however, are the properties of Xodol itself. Its chemical components’ interaction with the nervous system lead to physical addiction. Patients must follow the prescription instructions exactly when taking this drug. Without doing this, a patient might reach a stage where Xodol addiction treatment is necessary.

Treatment for Physical Addiction

Detoxification is required when a strong physical addiction has taken hold. While the drug remains in the bloodstream, it continues to stoke the addiction. Therefore, purging the painkiller is necessary for Xodol rehab to be successful. While the symptoms of withdrawal set forth above are common, other signs of discomfort may accompany withdrawal. They include:

  • Cramps
  • Chills
  • Mental confusion
  • Loss of coordination
  • Respiratory disruption

These withdrawal symptoms are best managed under the care and supervision of medical professionals experienced with Xodol addiction treatment. At times, substitute drugs, such as methadone, are administered to take the edge off the body’s reaction to Xodol detox.

Addressing Psychological Addiction

Addiction to strong opiates like Xodol has mental aspects as well as physical ones. Because of this, sufferers do well with a two-pronged approach to fight their dependency. In addition to detoxification, psychotherapy is an important tool for delving into the fears, connections, and world views that contribute to the cravings. Often, cognitive behavioral therapy is utilized in order to identify the dependent’s frame of mind when cravings are strongest.


  • Those who are allergic to acetaminophens, such as Tylenol, should not consume Xodol because they contain similar ingredients.
  • You should not consume Xodol if you drink three or more alcoholic beverages daily.

Harnessing the Power of Empathy

In order to maximize the benefits of Xodol addiction treatment, the patient should maintain regular contact with others who have experienced addiction. Getting assistance from others provides a form of mentoring by those who have been through the treatment and recovery process. This lets the less experienced person know that life without Xodol is possible. Also, getting support from former addicts takes the focus — if for only a short time — off the addict’s own struggles and allows him or her to think of the problems encountered by others. Finally, the recovering patient can experience the power of empathy from those who understand their plight. Forging relationships with supportive individuals is a strong motivator to stay clean. If you desire a comprehensive approach to Xodol addiction, call .

Was this page helpful?
Thank you for your feedback.

American Addiction Centers (AAC) is committed to delivering original, truthful, accurate, unbiased, and medically current information. We strive to create content that is clear, concise, and easy to understand.

Read our full editorial policy

While we are unable to respond to your feedback directly, we'll use this information to improve our online help.